Fill a form in 3 easy steps - less than 5 mins.
Posted: October 29th, 2022
Off-Label Drug Use in Pediatrics
Pediatrics prescribe medication for off-label drug use for a lack of specific medication to treat a certain ailment. Healthcare providers also prescribe drugs for off-label use due to a lack of adequate clinical trials on children (Gore et al., 2017). Lack of clinical trials presents a challenge of a lack of standard therapy to treat certain health conditions in children. Therefore, pediatricians will rely on sufficient research showing that certain medications can be used and positively impact a child’s health without negative effects (Gore et al., 2017). For instance, bupropion (Wellbutrin) is commonly used to treat depression, but it can be used to treat bipolar in off-label use (Gore et al., 2017). The decision to use it is due to the unavailability of effective alternatives and the positive impact of the drug on children.
The approaches to ensure safety of off-label use drugs is relying on evidence-based practice from clinical trials. They should acquire information from AAP policies, consensus statements, and clinical trials (Moulis et al., 2018). Other safety measures include checking the weight, health, and medical history of children (Moulis et al., 2018). The purpose is to take precautions to avoid adverse effects that may compromise the recovery process.
Pediatricians are aware that some medications require extra care to avoid adverse effects. One of the medications that require extra care is Quetiapine (Seroquel). The drug lead to a spike in blood pressure (Saiyed et al., 2017). Healthcare workers take precaution by checking blood pressure levels while administering the drug. Close monitoring is also necessary. Another medication is Montelukast (Singulair) that treats asthma. Children should start with a low dosage of the drug and get regular checkups (Saiyed et al., 2017). Pediatricians should ensure the benefits are more than the adverse effects that may affect the health of patients.
References
Gore, R., K Chugh, P., D Tripathi, C., Lhamo, Y., & Gautam, S. (2017). Pediatric off-label and unlicensed drug use and its implications. Current Clinical Pharmacology, 12(1), 18-25.
Moulis, F., Durrieu, G., & Lapeyre-Mestre, M. (2018). Off-label and unlicensed drug use in children population. Therapies, 73(2), 135-149.
Saiyed, M. M., Ong, P. S., & Chew, L. (2017). Off‐label drug use in oncology: a systematic review of literature. Journal of Clinical Pharmacy and Therapeutics, 42(3), 251-258.
You Want Quality and That’s What We Deliver
Our writing team is assembled through a rigorous selection process, where we handpick accomplished writers with specialized expertise in distinct subject areas and a proven track record in academic writing. Each writer brings a unique blend of knowledge and skills to the table, ensuring that our content is not only informative but also engaging and accessible to a general college student audience
Competitive pricing is a cornerstone of our service, where we balance affordability with exceptional quality. In offering the best writers at rates that rival other writing services, we ensure that students can access top-notch content without breaking the bank unnecessarily. Our fair and transparent pricing structure is designed to provide value for money, making us a go-to choice for students seeking high-quality writing services at an affordable price.
Academic integrity is paramount to our writing service, which is why we produce original research and writing content for every paper. Each piece of work is carefully written from scratch, ensuring that every sentence, paragraph, and page is authentic and free from plagiarism. Our rigorous quality control process involves thorough scanning of every final draft, guaranteeing that the content meets the highest standards of originality and academic integrity. With keen attention to citation and referencing, we ensure that every source is properly credited, giving you complete peace of mind. We also have the best plagiarism checkers like safeassign and turnitin thus providing similarity score for each paper.
When you decide to place an order with Dissertation Help, here is what happens: