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Posted: September 9th, 2022
Cholelithiasis (Gallstones) Disorder
Patient Scenario
The patient presented is a 42 years old woman with Native American origin. The symptoms include pain in the right upper quadrant which occurs main an hour after taking fatty meals and cabbage. She expresses obesity and features of poor dietary with excessive consumption of caffeine, fat and fatty products, and fast and fried meals. She indicated a high level of cholesterol and low-density lipoprotein.
Behavior Factors that Impacts Cholelithiasis
High consumption of high-fatted meals increases the chances of getting gallstones. High concentration results from the accumulation of cholesterol in the bile which increases the period at which the bile sits in the gallbladder leading to the formation of gallstone. It is evident that about 87 percent of the patients with gallstone and high serum LDL level results from the high accumulation of cholesterol (Atamanalp, Keles, Atamanalp, Acemoglu, & Laloglu, 2012). This condition can, however, be managed through controlling personal diet through a reduction in the consumption rate of caffeine, mono-saturated and poly-saturated fats.
Potential Associated Alterations and Symptoms
The disorder indicates asymptomatic and incidental symptoms. The patient experiences epigastric and hypochondrium pain. She frequently suffers from intolerance pain some minutes after consuming foods with cabbage and fats. This may be intermitted or constant, occurring in the right upper quadrant. Jaundice condition may be expressed when the stone stuck around the bile duct of the patient.
Pathophysiology and Cellular Function
Metabolisms processes within the gallbladder by the bile fluid prevents accumulation of fats and cholesterol in the body. Poor metabolism results in the formation of cholesterol, bilirubin, and gallstones (Huether & McCance, 2017). Production of excess cholesterol in the bile leads to saturation of the cholesterol in the gallbladder which forms cholesterol crystals which may accumulate and develop to a gallstone. The condition may result in complications like alteration of neural control, intrinsic muscle wall diseases or hormonal imbalance (Huether & McCance, 2017). The condition results to decrease in emptying rate of the gallbladder thus leading to an increased rate of formation of cholesterol macro stones or crystals which later develop into gallstone disorder.
References
Atamanalp, S. S., Keles, M. S., Atamanalp, R. S., Acemoglu, H., & Laloglu, E. (2012). The effects of serum cholesterol, LDL, and HDL levels on gallstone cholesterol concentration. Pakistan Journal of Medical Sciences, 29(1). doi:10.12669/pjms.291.2798
Hammer, G., & McPhee, S. J. (2014). Pathophysiology of Disease: An Introduction to Clinical Medicine Flash Cards: An Introduction to Clinical Medicine Flash Cards. New York, NY: McGraw Hill Professional.
Huether, S. E., & McCance, K. L. (2017). Understanding Pathophysiology (7th ed.). Maryland Heights, MO: Mosby.
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